Read recent publications from our members helping to strengthen innovative and multidisciplinary research on endocrine disruptors.


A Review of the Effects of the Biopesticides Bacillus thuringiensis Serotypes israelensis (Bti) and kurstaki (Btk) in Amphibians. Archives of Environmental Contamination and Toxicology, Empey MA, Lefebvre-Raine M, Gutierrez-Villagomez JM, Valerie S. Langlois, Vance L. Trudeau.

Agrochemicals disrupt multiple endocrine axes in amphibians. Molecular and Cellular Endocrinology, Vance L Trudeau, Paisley Thomson, Zhang WS, Stéphane Reynaud, Laia Navarro-Martin, Valérie S.Langlois.

A 30-Year Study of Impacts, Recovery, and Development of Critical Effect Sizes for Endocrine Disruption in White Sucker (Catostomus commersonii) Exposed to Bleached-Kraft Pulp Mill Effluent at Jackfish Bay, Ontario, Canada. Frontiers in Endocrinology. Erin Ussery, Mark McMaster, Mark Servos, David H. Miller and Kelly Munkittrick.

Changes to levels of microcontaminants and biological responses in rainbow trout exposed to extracts from wastewater treated by catalytic ozonation. Journal of Hazardous Materials, Chassaing FJ, Mahmudov R, Chris D.Metcalfe, Viviane Yargeau.

Developmental exposure to a POPs mixture or PFOS increased body weight and reduced swimming ability but had no effect on reproduction or behavior in zebrafish adults. Aquatic Toxicology, Christou M, Ropstad E, Brown S, Jorke H.Kamstra, Frasera TWK.

Disruption by stealth – Interference of endocrine disrupting chemicals on hormonal crosstalk with thyroid axis function in humans and other animals. Environmental Research, Anita Thambirajah, Michael G.Wade, Jonathan Verreault, Nicolas Buisine, Verônica A.Alves, Valerie S.Langlois, Caren C.Helbing.

Effects of an Environmentally Relevant Mixture of Organophosphate Esters Derived From House Dust on Endochondral Ossification in Murine Limb Bud Cultures. Toxicological Sciences, Yan H, Barbara Hales.

Effects of flame retardants on ovarian function. Reproductive Toxicology, Wang X, Barbara Hales, Bernard Robaire.

Elucidation of the Effects of Bisphenol A and Structural Analogs on Germ and Steroidogenic Cells Using Single Cell High-Content Imaging. Toxicological Sciences, Rajkumar A, Luu T, Beal MA, Tara Barton-Maclaren, Bernard Robaire, Barbara Hales.

Endocrine disruptors: Challenges and future directions in epidemiologic research. Environmental Research, Vikki Ho, Laura Pelland-St-Pierre, Sabrina Gravel, Maryse Bouchard, Marc-André Verner, Labrèche F.

Endocrine Disruptor Impacts on Fish From Chile: The Influence of Wastewaters. Frontiers in Endocrinology, Barra RO, Chiang G, Saavedra MF, Orrego R, Mark R. Servos, Hewitt LM, Mark E. McMaster, Bahamonde P, Tucca F, Kelly R. Munkittrick.

Exposure to Propylparaben During Pregnancy and Lactation Induces Long-Term Alterations to the Mammary Gland in Mice. Endocrinology, Mogus JP, LaPlante CD, Bansal R, Matouskova K, Schneider BR, Daniele E, Silva SJ, Hagen MJ, Dunphy KA, Jerry DJ, Schneider SS, Laura N Vandenberg.

Health status of fathead minnow (Pimephales promelas) populations in a municipal wastewater effluent-dominated stream in the Canadian prairies, Wascana Creek, Saskatchewan. Aquatic Toxicology, Hanson S, Steeves K, Bagatim T, Hogan N, Steve Wiseman, Hontela A, Giesy JP, Jones PD, Markus Hecker.

In Utero and Lactational Exposure to an Environmentally Relevant Mixture of Brominated Flame Retardants Induces a Premature Development of the Mammary Glands. Toxicological Sciences, Rita-Josiane Gouesse, Dianati E, Alec McDermott, Michael G Wade, Barbara Hales, Bernard Robaire, Isabelle Plante.

Non-targeted screening of trace organic contaminants in surface waters by a multi-tool approach based on combinatorial analysis of tandem mass spectra and open access databases. Talanta, Eysseric E, Beaudry F, Gagnon C, Pedro A. Segura.

Passive sampling and in vitro assays to monitor antiandrogens in a river affected by wastewater discharge. Science of The Total Environment. Elkayar K, Park JA, Pineda M, Westlund P, Viviane Yargeau.

Polybrominated Diphenyl Ethers in Human Follicular Fluid Dysregulate Mural and Cumulus Granulosa Cell Gene Expression. Endocrinology, Lefèvre PLC, Nardelli TC, Son, W-Y, Sadler AR, Rawn DFK, Goodyer C, Bernard Robaire, Barbara Hales.

Science, Consensus and Endocrine-Disrupting Chemicals: Re-thinking Disagreement in Expert Deliberations. Integrated Environmental Assessment and Management, Mcllroy-Young B, Annegaaike Leopold, Gunilla Öberg.

Time-dependent biological responses of juvenile yellow perch (Perca flavescens) exposed in situ to a major urban effluent. Ecotoxicology and Environmental Safety, Defo MA, Mercier L, Beauvais C, Brua R, Gerald Tétreault, Fontaine A, Couture P, Jonathan Verreault, Magali Houde.

The brominated flame retardant, TBCO, impairs oocyte maturation in zebrafish (Danio rerio). Aquatic Toxicology, Van Essen D, Alcaraz AJG, Miller JGP, Jones PD, Jon A.Doering, Steve Wiseman.

The male mammary gland: a novel target of endocrine disrupting chemicals. Reproduction, Szabo GK, Laura Vandenberg.

The manufacturing of consensus: A struggle for epistemic authority in chemical risk evaluation. Environmental Science & Policy, McIlroy-Young B, Gunilla Öberg, Annegaaike Leopold.

The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue. Nature Communications, Wang B, Tsakiridis EE, Zhang S, Llanos A, Desjardins EM, Yabut JM, Green AE, Day EA, Smith BK, Lally JSV, Wu J, Raphenya AR, Srinivasan KA, McArthur AG, Kajimura S, Patel JS, Michael G Wade, Morrison KM, Holloway AC, Steinberg GR.

Transgenerational effects of polychlorinated biphenyls: 2. Hypothalamic gene expression in rats. Biology of Reproduction, Gore AC, Thompson LM, Bell M, Jan A Mennigen.

Transgenerational metabolic disorders and reproduction defects induced by benzo[a]pyrene in Xenopus tropicalis. Environmental Pollution, Usal M, Veyrenc S, Ghitalla-Ciock MD, Regnault C, Sroda S, Fini JB, Canlet C, Tremblay-Franco M, Raveton M, Stéphane Reynaud.

Using Transcriptomics and Metabolomics to Understand Species Differences in Sensitivity to Chlorpyrifos in Japanese Quail and Double-Crested Cormorant Embryos. Environmental Toxicology and Chemistry, Desforges JP, Legrand E, Boulager E, Liu P, Xia J, Butler H, Chandramouli B, Ewald J, Niladri Basu, Markus Hecker, Jessica Head, Crump D.


Acute and long-term metabolic consequences of early developmental Bisphenol A exposure in zebrafish (Danio rerio). Chemosphere, Rubén Martínez, Tu W, Eng T, Allaire-Leung M, Piña B, Laia Navarro-Martín, Jan A. Mennigen.

Agrochemicals disrupt multiple endocrine axes in amphibians. Molecular and Cellular Endocrinology, Vance Trudeau, Paisley Thomson, Zhang WS, Stéphane Reynaud, Laia Navarro-Martin, Valérie Langlois.

A low-cost graphitized sand filter to deliver MC-LR-free potable water: Water treatment plants and household perspective. Science of the Total Environment, Pratik Kumar, Satinder Kaur Brar, Maximiliano Cledon.

An approach to classifying occupational exposures to endocrine disrupting chemicals by sex hormone function using an expert judgment process. Journal of Exposure Science & Environmental Epidemiology, Prichystalova R, Caron-Beaudoin E, Richardson L, Dirkx E, Amadou A, Zavodna T, Cihak R, Cogliano V, Hynes J, Laura Pelland-St-Pierre, Marc-André Verner, van Tongeren M, Vikki Ho.

An early-life stage alternative testing strategy for assessing the impacts of environmental chemicals in birds. Environmental Toxicology and Chemistry, Farhat A, Boulanger E, Bidinosti L, Niladri Basu, Markus Hecker, Crump D, Jessica Head.

Application of in vitro bioassays for water quality monitoring in three drinking water treatment plants using different treatment processes including biological treatment, nanofiltration and ozonation coupled with disinfection. Environmental Science: Water Research & Technology, Neale P, Feliers C, Glauch L, Lecarpentier C, Schlichting R, Thibert S, Beate Escher.

Bisphenol A and bisphenol S disruptions of the mouse placenta and potential effects on the placenta-brain axis. Proc Natl Acad Sci U S A, Mao J, Jain A, Nancy Denslow, Nouri MZ, Chen S, Wang T, Zhu N, Koh J, Sarma SJ, Sumner BW, Lei Z, Sumner LW, Bivens NJ, Roberts RM, Tuteja G, Rosenfeld CS.

Bisphenol A and S impaired ovine granulosa cell steroidogenesis. Reproduction. Téteau O, Jaubert M, Desmarchais A, Papillier P, Binet A, Virginie Maillard.

Bisphenol S Impaired In Vitro Ovine Early Developmental Oocyte Competence. International Journal of Molecular Sciences, Desmarchais A, Téteau O, Papillier P, Jaubert M, Druart X, Binet A, Virginie Maillard, Elis S.

Calcium signaling as a possible mechanism behind increased locomotor response in zebrafish larvae exposed to a human relevant persistent organic pollutant mixture or PFOS. Environmental Research, Christou M, Fraser T.W.K, Berg V, Ropstad E, Jorke Kamstra.

Consequences of steroid-5α-reductase deficiency and inhibition in vertebrates. General and Comparative Endocrinology, Julie Robitaille, Valérie Langlois.

Depot-Specific Analysis of Human Adipose Cells and Their Responses to Bisphenol S. Endocrinology, Peshdary V, Styles G, Gagné R, Carole L Yauk, Sorisky A, Ella Atlas.

Development of an estrogen-dependent breast cancer co-culture model as a tool for studying endocrine disruptors. Toxicol In Vitro, Yancu D, Viau R, Thomas Sanderson.

Effects of brominated and organophosphate ester flame retardants on male reproduction. Andrology, Barbara Hales, Bernard Robaire.

Effects of cadmium, inorganic mercury and methyl-mercury on the physiology and metabolomic profiles of shoots of the macrophyte Elodea nuttallii. Environmental Pollution Journal, Cosio C., David Renault.

Effects of DEHP on the ecdysteroid pathway, sexual behavior and offspring of the moth Spodoptera littoralis. Hormones and Behavior Journal. Avilès A, Cordeiro A, Maria A, Bozzolan F, Boulogne I, Dacher M, Goutte A, Alliot F, Maibeche M, Massot M, David Siaussat.

Emerging Links between Cadmium Exposure and Insulin Resistance: Human, Animal, and Cell Study Data. Toxics. Aleksandra Buha Djordjevic, Đukić-Ćosić, D., Ćurčić, M., Bulat, Z., Antonijević, B., Moulis, J.-M., Goumenou, M., Wallace, D.

Endocrine-disrupting chemicals: economic, regulatory, and policy implications. Lancet Diabetes and Endocrinology. Kassotis C.D, Vanderberg L.N, Barbara Demeneix, Porta M, Slama R, Transande L.

Environmentally relevant mixture of S-metolachlor and its two metabolites affects thyroid metabolism in zebrafish embryos. Aquatic Toxicology, Rozmankova E, Pipal M, Blahova L, Njattuvetty Chandran N, Morin B, Patrice Gonzalez, Blaha L.

Essential oils disrupt steroidogenesis in a feto-placental co-culture model. Reproductive Toxicology, Yancu D, Thomas Sanderson.

Exposure to Low Doses of Dechlorane Plus Promotes Adipose Tissue Dysfunction and Glucose Intolerance in Male Mice. Endocrinology, Peshdary V, Styles G, Rigden M, Caldwell D, Kawata A, Sorisky A, Ella Atlas.

Exposure to tert-Butylphenyl Diphenyl Phosphate, an Organophosphate Ester Flame Retardant and Plasticizer, Alters Hedgehog Signaling in Murine Limb Bud Cultures. Toxicological Sciences, Yan H, Barbara Hales.

Faut-il dé(cons)truire les problèmes publics ? Réflexions à partir d’une recherche sur les pollutions de «l’air intérieur». Politique et Sociétés, Ferron B, Jean-Pierre Le Bourhis.

In Utero and Lactational Exposure to Flame Retardants Disrupts Rat Ovarian Follicular Development and Advances Puberty. Toxicological Sciences, Allais A, Albert O, Lefèvre PLC, Michael G Wade, Barbara Hales, Bernard Robaire.

Invertebrates facing environmental contamination by endocrine disruptors: Novel evidences and recent insights. Molecular and Cellular Endocrinology, Virginie Cuvillier-Hot, Lenoir A.

Lethal and sublethal toxicity of perfluorooctanoic acid (PFOA) in chronic tests with Hyalella azteca (amphipod) and early-life stage tests with Pimephales promelas (fathead minnow). Ecotoxicology and Environmental Safety, Bartlett AJ, De Silva AO, Schissler DM, Hedges AM, Brown LR, Shires K, Miller J, Sullivan C, Spencer C, Joanne Parrott.

Long-term and comparative impacts of combined sewers and municipal effluents to freshwater mussels. Invertebrate Survival Journal, André C, Vaudreuil M.-A, Vo Duy S, François gagné, Sébastien Sauvé.

Non-steroidal anti-inflammatory drugs in the Environment: Where were we and how far we have come?. Environmental Pollution, Izadi Parnian, Izadi Parin, Salem R, Sifat Azad Papry, Magdouli S, Rama Pulicharla, Satinder Kaur Brar.

Organochlorine pesticides: Agrochemicals with potent endocrine-disrupting properties in fish. Molecula and Cellular Endocrinology. Christopher J. Martyniuk, Mehinto AC, Nancy Denslow.

Quantification of steroid hormones in low volume plasma and tissue homogenates of fish using LC-MS/MS. Gen Comp Endocrinol, Nouri MZ, Kroll KJ, Webb M, Nancy Denslow.

Removal of Microcystin-LR and other water pollutants using sand coated with bio-optimized carbon submicron particles: graphene oxide and reduced graphene oxide. Chemical Engineering Journal, Pratik Kumar, José Alberto Espejel Pérez, Maximiliano Cledon, Satinder Kaur Brar, Sung Vo Duy, Sébastien Sauvé, Émile Knystautas.

Steroidogenic Acute Regulatory Protein Transcription is Regulated by Estrogen Receptor Signaling in Largemouth Bass Ovary. General and Comparative Endocrinology, Prucha MS, Chritopher J. Martyniuk, Doperalski NJ, Kroll KJ, Barber DS, Nancy Denslow.

Steroid hormones and estrogenic activity in the wastewater outfall and receiving waters of the Chascomús chained shallow lakes system (Argentina). The Science of the Total Environment, González A, Kroll KJ, Silva-Sanchez C, Juan Fernandino, Nancy Denslow, Carriquiriborde P, Somoza GM.

Suspected-target screening for the assessment of plastic-related chemicals in honey. Food Control, von Eyken A, Ramachandran S, Stéphane Bayen.

Techno-economic assessment of an hydrometallurgical process to simultaneously remove As, Cr, Cu, PCP and PCDD/F from contaminated soil. Journal of Environmental Management, Metahni S, Coudert L, Jean-François Blais, Tran L.H, Gloaguen E, Mercier Ga, Mercier G.

The comparative toxicity of rainfall overflows and a municipal effluent plume in Elliptio complanata using a novel qPCR array approach. Comp Biochem Physiol C Toxicol Pharmacol, André C, François Gagné.

The GOLIATH Project: Towards an Internationally Harmonised Approach for Testing Metabolism Disrupting Compounds. International Journal of Molecular Sciences, Legler J, Zalko D, Jourdan F, Jacobs M, Fromenty B, Balaguer P, Bourguet W, Munic Kos V, Nadal A, Beausoleil C, Cristobal S, Remy S, Ermler S, Margiotta-Casaluci L, Griffin J.L, Blumberg B, Chesné C, Hoffmann S, Andersson P.L, Jorke Kamstra.

The impact and toxicity of glyphosate and glyphosate-based herbicides on health and immunity. Journal of Immunotoxicology, Cindy Peillex, Martin Pelletier.

Thermal degradation of bisphenol A and bisphenol S in water and fish (cod and basa) fillets. Food Chemistry, Tian L, Goodyer C, Zheng J, Stéphane Bayen.

Transcriptomic effects of tributyltin (TBT) in zebrafish eleutheroembryos. A functional benchmark dose analysis. Journal of Hazardous Materials, Ruben Martínez, Codina A.E, Barata C, Tauler R, Piña B, Laia Navarro-Martín.

Twenty years of transcriptomics, 17alpha-ethynylestradiol, and fish. General and Comparative Endocrinology, Christopher J. Martyniuk, Feswick A, Kelly Munkittrick, Dreier DA, Nancy Denslow.

Utility of a multi-tracer approach as a component of adaptive monitoring for municipal wastewater impacts. Water Quality Reasearch Journal, Rajiv Neal Tanna, Moncur MC, Birks SJ, Gibson JJ, Ptacek CJ, Mayer B, Weiser MF, Wrona FJ, Kelly Munkittrick.